Coronavirus in vitro transcription of RNA standard material can reduce the probability of "false negative"

According to the Shanghai Municipal Market Supervision Bureau, the "New Coronavirus In Vitro Transcription RNA Standard Material" developed in Shanghai has recently been approved as a national standard material, which can effectively evaluate the accuracy of the new coronavirus nucleic acid detection kit. This is the first novel coronavirus in vitro transcription RNA standard material successfully developed locally and approved by the state, which can be used by domestic and foreign nucleic acid kit manufacturers and R&D institutions, shortening the development and approval time of nucleic acid kits from more than one year to two months.

The "New Coronavirus In Vitro Transcription RNA Reference Material" was developed by the biometric team of the Shanghai Institute of Metrology and Testing Technology under the Shanghai Municipal Market Supervision Bureau. The laboratory staff introduced that the "New Coronavirus In Vitro Transcription RNA Reference Material" is a liquid, usually Store on dry ice and maintain a temperature of minus 20°C during transport. This standard material can effectively evaluate the accuracy of the new coronavirus nucleic acid detection kit, and greatly reduce the probability of "false negatives". "

The so-called new coronavirus in vitro transcription RNA reference material is actually a special social public measurement standard. For example, weight is also a social public measurement standard. A standard weight can detect whether a balance is accurate. In the same way, with the "new coronavirus in vitro transcription RNA standard material", the new coronavirus nucleic acid detection kit can be measured.

It is reported that the current production volume of this standard substance can reach 1,000 sets/day, and it can be stably delivered to manufacturing enterprises and testing laboratories nationwide to provide quantitative support for nucleic acid detection of the new coronavirus. Currently, it is exported to support South Korea, Italy and other countries. The detection technology adopts the RNA standard material developed this time, which provides accurate measurement support for the development and application of high-level analysis methods in China and its international assistance.

In terms of the promotion of "New Coronavirus In Vitro Transcription RNA Reference Material", a large number of customers have put forward demands. The main groups of customers are the R&D teams of kit R&D companies and scientific research institutes. It is expected that there will be more customers in the future.