Weiyel Precision Diagnostics for Nipah Virus: Integrated Solution for Quality Control Products and Reagent Kits

Recently, the Nipah virus outbreak in West Bengal, eastern India, has continued to escalate, with 5 confirmed cases, including several healthcare workers. Nearly 200 people have been placed under quarantine, and local hospitals have entered a state of emergency. As a deadly zoonotic virus listed by the WHO as a high-risk pandemic pathogen, Nipah virus uses fruit bats as its natural host and can be transmitted from person to person through contaminated food and close contact. Its incubation period can be as long as 45 days, with a mortality rate as high as 40%-75%. Currently, there are no specific vaccines or treatments, making accurate and rapid detection crucial to curbing the spread of the epidemic.

In response to the current severe situation, Weiyel has simultaneously launched Nipah virus N-gene pseudovirus quality control products and Nipah virus nucleic acid detection kits (fluorescent PCR method), forming a closed-loop solution of "detection + quality control." This provides efficient and reliable technical support for clinical diagnosis and disease control monitoring, strengthening the first line of defense against the epidemic.

Core Product Advantages, Collaborative Empowerment for Precision Prevention and Control

Pseudovirus Control Products: Safe, accurate, stable, and traceable. Targeting the Nipah virus N gene to construct a pseudovirus structure, containing no active viral components, requiring no Biosafety Level 4 laboratory protection, avoiding the risks of handling live viruses, and suitable for disease control, medical institutions, and research laboratories at all levels. Utilizing digital PCR technology for multi-laboratory joint determination, resulting in excellent uniformity of values ​​and strong resistance to nuclease degradation. It realistically simulates the extraction and amplification process of viral nucleic acid in samples, providing a traceable standard for reagent kit performance evaluation, instrument calibration, and laboratory quality control, ensuring accurate and consistent test results.

Reagent Kits: Highly efficient, sensitive, and easy to use. Developed based on a fluorescence PCR technology platform, it uses specific primers and probes designed to target the conserved sequence of Nipah virus, accurately capturing low concentrations of viral nucleic acid, effectively shortening the detection window period and reducing the risk of false negatives. Employing a one-tube fully premixed lyophilization process, it eliminates the need for complex solution preparation; sample addition is sufficient for immediate testing, with amplification and detection completed within 1 hour. Compatible with mainstream fluorescence PCR instruments both domestically and internationally, it also includes a built-in endogenous internal standard for full monitoring of the sampling, extraction, and amplification process, eliminating false negative results.

Diverse Application Scenarios, Covering the Entire Prevention and Control Chain

In clinical diagnosis and treatment, the kits can rapidly screen suspected cases, buying time for the treatment of critically ill patients. Simultaneously, the pseudovirus quality control products ensure the accuracy of diagnostic results, preventing the spread of the epidemic due to misdiagnosis or missed diagnosis.

In disease control and port control, large-scale population screening and virus epidemic monitoring can be carried out. The quality control products calibrate the entire testing process, ensuring the uniformity and comparability of cross-regional monitoring data.

Furthermore, both can be used in conjunction for research institutions' detection technology development, kit performance verification, and third-party testing institutions' laboratory capability assessment, providing core tools for Nipah virus prevention and control technology innovation and standardization.

Safeguarding Public Health Security with Closed-Loop Technology
Weiyel's Nipah Virus N-Gene Pseudovirus Quality Control Products and Nucleic Acid Detection Kits (Fluorescent PCR Method), with their synergistic advantages of "high-efficiency detection + precise quality control," help improve emergency response capabilities for epidemics. Facing global public health security challenges, we will continue to deepen our expertise in pathogen detection and quality control, using our professional strength to build a solid public health security barrier and protect human health.